What is the main difference between HIV-1 and HIV-2?

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HIV stands for Human Immunodeficiency Virus. There are mainly two types of HIV: HIV-1 and HIV-2. Both are different virus. HIV-1 is most common and pathogenic strain of HIV type but HIV-2 is mainly seen in West African  Countries. The first person in United State was found infected by HIV-2 in 1987.

The HIV-2 infection spread in the rest of the world is negligible and it progresses very slow than HIV-1.

HIV-2 often is less infectious early in the course of infection and, compared to HIV-1, the duration of increased infectiousness is shorter.

Both HIV types have same transmission process like transmitted through blood and sexual contact etc. HIV-2 has been found to be less pathogenic than HIV-1.

HIV Transmission

HIV-1 enters the immune system by attaching onto the CD4+ receptor found on the surface of certain white blood cells. HIV-2 has a harder time gaining such a foothold.

According to both structure, HIV2 contains certain protein molecules but that are not present in HIV-1.

Both HIV viruses are unreliable and highly susceptible to physical as well as chemical agents and therefore do not survive well outside the human body.


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